1From Albania to Silicon Valley
Mira Murati was born in December 1988 in Vlorë, Albania, during the final years of the country's totalitarian communist regime. Her early years were shaped by political upheaval—her family eventually moved to Canada when she was a teenager.
She pursued an unconventional dual-degree path: a Bachelor of Arts in Mathematics from Colby College and a Bachelor of Engineering in Mechanical Engineering from Dartmouth's Thayer School. This combination of pure math and applied engineering would define her approach to AI.
"I've always been interested in how things work at a fundamental level—whether that's mathematics or machines. AI sits at the intersection of both."
— Mira Murati
2The OpenAI Years
Murati joined OpenAI in June 2018 as Vice President of Applied AI and Partnerships. She quickly rose through the ranks—Senior VP by 2020, then Chief Technology Officer in 2022. Under her technical leadership, OpenAI shipped the products that defined the AI era.
She led the teams that built ChatGPT, DALL-E, Codex, and Sora. These weren't just research papers—they were products that reached hundreds of millions of users. ChatGPT became the fastest-growing consumer application in history.
3The Decision to Leave
In September 2024, at the peak of OpenAI's success, Murati announced she was stepping down as CTO. The tech world was stunned. Why leave the most important AI company in the world?
Her explanation was simple: she wanted to explore. After years of executing within OpenAI's vision, she wanted to build her own. The departure came amid leadership turbulence at OpenAI, but Murati's exit was about creation, not escape.
Most people cling to success. Murati understood that staying at OpenAI meant executing someone else's vision forever. Sometimes the boldest move is leaving when you're winning.
4Thinking Machines Lab
In February 2025, Murati launched Thinking Machines Lab as a public benefit corporation. The mission: make AI systems more understandable, customizable, and generally capable. She wasn't just building another AI company—she was addressing the problems she saw from inside OpenAI.
She recruited a team of about 30 leading researchers from Meta, Mistral, and OpenAI—including OpenAI co-founder John Schulman. Advisors include Alec Radford and Bob McGrew. This wasn't a startup; it was a dream team.
The Seed Round:
$2 billion raised at $12 billion valuation—the largest seed round in venture capital history. Led by Andreessen Horowitz, with Nvidia, Accel, and AMD.
First Product:
Tinker—a Python API for fine-tuning language models. Making frontier AI tools accessible to researchers everywhere.
5Key Lessons for Founders
1. Execution builds reputation
Murati raised $2B before shipping a product because she'd already shipped ChatGPT, DALL-E, and Sora. Your track record is your pitch deck.
2. Leave at the top
She left OpenAI as CTO, not after a failure. Leaving from strength gives you leverage to build something new.
3. Recruit the believers
Murati brought top talent from OpenAI, Meta, and Mistral. Great founders attract great people. Your network is your unfair advantage.
4. Mission matters
Thinking Machines Lab is a public benefit corporation. In AI, trust and mission alignment can be competitive advantages.
5. Constraints breed clarity
Growing up in post-communist Albania shaped Murati's resilience. Your background isn't a limitation—it's perspective others don't have.